In this assignment, you are to write a 5- to 6-page paper in which you discuss each of the following mood stabilizer medications: carbamazepine, lamotrigine, lithium, and valproate products. (Please note that your title page and reference page(s) do NOT count towards your total page count.) Your paper must include the following information for each medication:
1. Proposed mechanism of action
2. Baseline assessment, laboratory considerations, and frequency of ongoing labs and assessments. *Note: You must discuss the importance of assessment and labs.
3. Special population considerations (birth assigned gender, age, other medical comorbidity considerations)
4. FDA-approved indications
5. Typical dosing with discussion on therapeutic endpoints for psychiatric use
Your paper must also include a discussion on the following:
A. Major drug–drug interaction considerations
o For each of these medications, please review the potential drug–drug interactions listed below. Consider alternative dosing schedules, clinical implications for the drug interactions, additional patient education needed, any additional monitoring recommended, or collaboration needed with other medical professions (such as, primary care providers)
• Lamotrigine + Valproate
• Lamotrigine + Rifampin
• Valproate + Estrogen containing birth control.
• Valproate + Amitriptyline
• Lithium + Furosemide
• Lithium + Lisinopril
• Carbamazepine + Lurasidone
• Carbamazepine + Grapefruit juice
B. Discuss the ethical, legal, and social implications related to prescribing bipolar and other related mood-disorder diagnoses therapy for patients.
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